This report was designed to investigate the propranolol use in a psychiatric in-patients unit. All of patients who had admitted to department of psychiatry of Yonsei University. Wonju Christian Hospital. From Jan. 1st to Dec. 31st 1990. Were
included in
this investigation. The propranolol was prescribed in the 107 patients (69male patients and 38 female patients) among the total 147 patients.
@ES The results were as the followings:
@EN 1) The propranolol was prescribed in 23.9% of the 447 patients.
2) The patients whose initial daily dosage of the propranolol was between 40mg and 80mg, were 77.6% of the total patients, and the average dosage was 52.1±24.4mg.
3) The daily dosage of the prescribed propranolol ranged from 20mg to 440mg. The maximal dosage was 106.6±82.2mg/
4) Schizophrenia was highest diagnostic group(37.4%) among all DSM-III-R diagnostic distribution in the patients with the propranolol.
5) Symptom improvement was the main reason of limited-increase pattern of administration(46.7%). 35 patients failed to continue propranolol use 22 patients(62.9%) among them had stopped propranolol use because of some kind of side effects.
6) Propranolol was effective in 80.4% of the patients for the target symptoms.
7) The target symptoms for the propranolol use were aggression, anxiety, akathisia, mania. Psychosis and tremor. Akathisia(39 patients. 36.4%) was the most frequent reason of propranolol administration, the next was anxiety(30 patients. 28.0%),
thereafter aggression(27 patients, 25.2%). The above 3 groups account for almost target symptoms(89.7%).
8) The maximal dosage for aggression was 191.9mg in average, and significantly higher than that for anxiety(98.3%), akathisia(61.5mg) and tremor(56.0mg).
9) With the target symptoms of the propranolol use, the pattern of propranolol administration varied by one of three modes.
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